Clinico-Epidemiological Features and Survival Outcome in Patients with NSCLC: Ain Shams Clinical Oncology Department 5-Year Data

Ahmed Nagy; Mohamed Kelney

doi:doi:10.11648/j.crj.20190702.14

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Clinico-Epidemiological Features and Survival Outcome in Patients with NSCLC: Ain Shams Clinical Oncology Department 5-Year Data

Ahmed Nagy, Mohamed Kelney

Published in Cancer Research Journal (Volume 7, Issue 2)

Received: 28 April 2019 Accepted: 10 June 2019 Published: 24 June 2019

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Abstract

Background: Primary lung cancer is the most common malignant neoplasm worldwide with various prognostic factors. Methods: Data was analysed retrospectively from the medical records of 504 patients diagnosed with NSCLC and treated at Department of Clinical Oncology and Nuclear Medicine, Ain Shams University, Cairo-Egypt in the period from 1-1-2008 till 31-12- 2012. Results: The Median PFS after first, second and third lines was 3, 4 and 2 months respectively and the median OS was 8 months. Factors which were associated with a statistically significant difference in median OS were: age<60 years versus≥60 years (10 and 7 months respectively, p<0.001), female versus male gender (10 and 8 months respectively, p<0.001), urban versus rural residence (9 and 8 months respectively, p=0.03), smokers versus non-smokers (8 and 10 months respectively, p<0.001), patients presenting with non-neurological symptoms and those presenting with neurological symptoms (9 and 6 months respectively, p<0.001) and the receiving treatment versus no treatment (10 and 5 months respectively, p<0.001). Conclusion: This study shows that the active treatment of patients with NSCLC continues to have an important impact on survival. The fact that rural residence could be associated with worse OS warrants further investigation.

Published in	Cancer Research Journal (Volume 7, Issue 2)
DOI	10.11648/j.crj.20190702.14
Page(s)	53-57
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

NSCLC, Adenocarcinoma, Lung, Cancer

References

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APA Style

Ahmed Nagy, Mohamed Kelney. (2019). Clinico-Epidemiological Features and Survival Outcome in Patients with NSCLC: Ain Shams Clinical Oncology Department 5-Year Data. Cancer Research Journal, 7(2), 53-57. https://doi.org/10.11648/j.crj.20190702.14

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ACS Style

Ahmed Nagy; Mohamed Kelney. Clinico-Epidemiological Features and Survival Outcome in Patients with NSCLC: Ain Shams Clinical Oncology Department 5-Year Data. Cancer Res. J. 2019, 7(2), 53-57. doi: 10.11648/j.crj.20190702.14

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AMA Style

Ahmed Nagy, Mohamed Kelney. Clinico-Epidemiological Features and Survival Outcome in Patients with NSCLC: Ain Shams Clinical Oncology Department 5-Year Data. Cancer Res J. 2019;7(2):53-57. doi: 10.11648/j.crj.20190702.14

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@article{10.11648/j.crj.20190702.14,
  author = {Ahmed Nagy and Mohamed Kelney},
  title = {Clinico-Epidemiological Features and Survival Outcome in Patients with NSCLC: Ain Shams Clinical Oncology Department 5-Year Data},
  journal = {Cancer Research Journal},
  volume = {7},
  number = {2},
  pages = {53-57},
  doi = {10.11648/j.crj.20190702.14},
  url = {https://doi.org/10.11648/j.crj.20190702.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20190702.14},
  abstract = {Background: Primary lung cancer is the most common malignant neoplasm worldwide with various prognostic factors. Methods: Data was analysed retrospectively from the medical records of 504 patients diagnosed with NSCLC and treated at Department of Clinical Oncology and Nuclear Medicine, Ain Shams University, Cairo-Egypt in the period from 1-1-2008 till 31-12- 2012. Results: The Median PFS after first, second and third lines was 3, 4 and 2 months respectively and the median OS was 8 months. Factors which were associated with a statistically significant difference in median OS were: ageppp=0.03), smokers versus non-smokers (8 and 10 months respectively, ppp<0.001). Conclusion: This study shows that the active treatment of patients with NSCLC continues to have an important impact on survival. The fact that rural residence could be associated with worse OS warrants further investigation.},
 year = {2019}
}

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TY  - JOUR
T1  - Clinico-Epidemiological Features and Survival Outcome in Patients with NSCLC: Ain Shams Clinical Oncology Department 5-Year Data
AU  - Ahmed Nagy
AU  - Mohamed Kelney
Y1  - 2019/06/24
PY  - 2019
N1  - https://doi.org/10.11648/j.crj.20190702.14
DO  - 10.11648/j.crj.20190702.14
T2  - Cancer Research Journal
JF  - Cancer Research Journal
JO  - Cancer Research Journal
SP  - 53
EP  - 57
PB  - Science Publishing Group
SN  - 2330-8214
UR  - https://doi.org/10.11648/j.crj.20190702.14
AB  - Background: Primary lung cancer is the most common malignant neoplasm worldwide with various prognostic factors. Methods: Data was analysed retrospectively from the medical records of 504 patients diagnosed with NSCLC and treated at Department of Clinical Oncology and Nuclear Medicine, Ain Shams University, Cairo-Egypt in the period from 1-1-2008 till 31-12- 2012. Results: The Median PFS after first, second and third lines was 3, 4 and 2 months respectively and the median OS was 8 months. Factors which were associated with a statistically significant difference in median OS were: ageppp=0.03), smokers versus non-smokers (8 and 10 months respectively, ppp<0.001). Conclusion: This study shows that the active treatment of patients with NSCLC continues to have an important impact on survival. The fact that rural residence could be associated with worse OS warrants further investigation.
VL  - 7
IS  - 2
ER  -

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Author Information

Ahmed Nagy

Department of Clinical Oncology and Nuclear Medicine, Ain Shams University Faculty of Medicine, Cairo, Egypt
Mohamed Kelney

Department of Clinical Oncology and Nuclear Medicine, Ain Shams University Faculty of Medicine, Cairo, Egypt

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APA Style

Ahmed Nagy, Mohamed Kelney. (2019). Clinico-Epidemiological Features and Survival Outcome in Patients with NSCLC: Ain Shams Clinical Oncology Department 5-Year Data. Cancer Research Journal, 7(2), 53-57. https://doi.org/10.11648/j.crj.20190702.14

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ACS Style

Ahmed Nagy; Mohamed Kelney. Clinico-Epidemiological Features and Survival Outcome in Patients with NSCLC: Ain Shams Clinical Oncology Department 5-Year Data. Cancer Res. J. 2019, 7(2), 53-57. doi: 10.11648/j.crj.20190702.14

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AMA Style

Ahmed Nagy, Mohamed Kelney. Clinico-Epidemiological Features and Survival Outcome in Patients with NSCLC: Ain Shams Clinical Oncology Department 5-Year Data. Cancer Res J. 2019;7(2):53-57. doi: 10.11648/j.crj.20190702.14

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@article{10.11648/j.crj.20190702.14,
  author = {Ahmed Nagy and Mohamed Kelney},
  title = {Clinico-Epidemiological Features and Survival Outcome in Patients with NSCLC: Ain Shams Clinical Oncology Department 5-Year Data},
  journal = {Cancer Research Journal},
  volume = {7},
  number = {2},
  pages = {53-57},
  doi = {10.11648/j.crj.20190702.14},
  url = {https://doi.org/10.11648/j.crj.20190702.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20190702.14},
  abstract = {Background: Primary lung cancer is the most common malignant neoplasm worldwide with various prognostic factors. Methods: Data was analysed retrospectively from the medical records of 504 patients diagnosed with NSCLC and treated at Department of Clinical Oncology and Nuclear Medicine, Ain Shams University, Cairo-Egypt in the period from 1-1-2008 till 31-12- 2012. Results: The Median PFS after first, second and third lines was 3, 4 and 2 months respectively and the median OS was 8 months. Factors which were associated with a statistically significant difference in median OS were: ageppp=0.03), smokers versus non-smokers (8 and 10 months respectively, ppp<0.001). Conclusion: This study shows that the active treatment of patients with NSCLC continues to have an important impact on survival. The fact that rural residence could be associated with worse OS warrants further investigation.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - Clinico-Epidemiological Features and Survival Outcome in Patients with NSCLC: Ain Shams Clinical Oncology Department 5-Year Data
AU  - Ahmed Nagy
AU  - Mohamed Kelney
Y1  - 2019/06/24
PY  - 2019
N1  - https://doi.org/10.11648/j.crj.20190702.14
DO  - 10.11648/j.crj.20190702.14
T2  - Cancer Research Journal
JF  - Cancer Research Journal
JO  - Cancer Research Journal
SP  - 53
EP  - 57
PB  - Science Publishing Group
SN  - 2330-8214
UR  - https://doi.org/10.11648/j.crj.20190702.14
AB  - Background: Primary lung cancer is the most common malignant neoplasm worldwide with various prognostic factors. Methods: Data was analysed retrospectively from the medical records of 504 patients diagnosed with NSCLC and treated at Department of Clinical Oncology and Nuclear Medicine, Ain Shams University, Cairo-Egypt in the period from 1-1-2008 till 31-12- 2012. Results: The Median PFS after first, second and third lines was 3, 4 and 2 months respectively and the median OS was 8 months. Factors which were associated with a statistically significant difference in median OS were: ageppp=0.03), smokers versus non-smokers (8 and 10 months respectively, ppp<0.001). Conclusion: This study shows that the active treatment of patients with NSCLC continues to have an important impact on survival. The fact that rural residence could be associated with worse OS warrants further investigation.
VL  - 7
IS  - 2
ER  -

Copy | Download