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Research Article |

Effects of Aqueous Extract of Tetracarpidium conophorum (Mull. Arg.) & Hutch Kernels on Semen Quality and Oxidative Stress Parameters in Male Rats

The aim of the present study was to evaluate the effects of the aqueous extract of Tetracarpidium conophorum kernels on semen quality and oxidative stress parameters in male rats. 20 rats were randomly divided into 4 lots of 5 animals each, and lots 1 and 2 were given distilled water and the reference molecule for 28 days, while lots 3 and 4 were treated with the aqueous extract of Tetracarpidium conophorum kernels (250 and 500 mg/kg/po). The results show that administration of aqueous extract of Tetracarpidium conophorum kernels (250 and 500 mg/kg/po) to rats produced significant dose-dependent increases (p < 0.05; p < 0.01) in sperm count and motility compared with the control lot treated with distilled water. On the other hand, pH and sperm vitality showed no significant variation (p > 0.05). Administration of the aqueous extract of Tetracarpidium conophorum kernels at the doses studied resulted in no significant variation (p > 0.05) in MDA and CAT concentrations compared with distilled water. However, there was a significant increase (p < 0.05; p < 0.001) in GSH, and GPX concentrations at the respective doses of 500, 250 and 500 mg/kg of Tetracarpidium conophorum aqueous extract compared to rats given distilled water. Chemical analysis of the aqueous extract of Tetracarpidium conophorum kernels revealed the presence of polyphenols and total flavonoids with anti-free radical and antioxidant effects. These results suggest that the aqueous extract of Tetracarpidium conophorum may have spermatogenic and antioxidant potential.

Tetracarpidium conophorum, Oxidative Stress, Semen

APA Style

Herman, A., Landry, M. M., Gallo, M. D. -. B., Stéphane, W. L. B., Moukouma, C., et al. (2023). Effects of Aqueous Extract of Tetracarpidium conophorum (Mull. Arg.) & Hutch Kernels on Semen Quality and Oxidative Stress Parameters in Male Rats. American Journal of BioScience, 11(6), 164-170. https://doi.org/10.11648/j.ajbio.20231106.15

ACS Style

Herman, A.; Landry, M. M.; Gallo, M. D. -. B.; Stéphane, W. L. B.; Moukouma, C., et al. Effects of Aqueous Extract of Tetracarpidium conophorum (Mull. Arg.) & Hutch Kernels on Semen Quality and Oxidative Stress Parameters in Male Rats. Am. J. BioScience 2023, 11(6), 164-170. doi: 10.11648/j.ajbio.20231106.15

AMA Style

Herman A, Landry MM, Gallo MD-B, Stéphane WLB, Moukouma C, et al. Effects of Aqueous Extract of Tetracarpidium conophorum (Mull. Arg.) & Hutch Kernels on Semen Quality and Oxidative Stress Parameters in Male Rats. Am J BioScience. 2023;11(6):164-170. doi: 10.11648/j.ajbio.20231106.15

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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