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Research Progress and Controversy on the Relationship Between Iodine Excess and Thyroid Cancer Occurrence

Thyroid cancer is the most common thyroid malignant tumor, and its incidence rate is on the rise in most countries. Iodine is an essential trace element for the synthesis of thyroid hormones in the human body. Long term excessive iodine can induce thyroid diseases such as hyperthyroidism and thyroid nodules, but its relationship with the occurrence of thyroid cancer is uncertain. There may be regional differences and some confusing or interfering factors, due to the influence of iodine intake and dietary habits on the final iodine nutritional status of the human body, and the influence of water iodine content on the iodine nutritional status of the human body. In recent years, researchers have revealed the relationship between iodine excess and thyroid cancer through ecological studies of regional water iodine distribution, dietary iodine and thyroid cancer, but the results are controversial. In the epidemiological studies on the correlation between urinary iodine concentration and thyroid cancer in residents, there is no conclusion on the correlation between urinary iodine concentration and iodine level of thyroid cancer patients and whether MUI can truly reflect the iodine nutrition level of thyroid cancer patients. This article reviews the research progress and controversies on the relationship between iodine excess and thyroid cancer, and comments on the possible reasons for the controversies, providing reference for future research.

Iodine, Thyroid Cancer, TSH, BRAF

APA Style

Feng, Z., Na, L., Guiran, Y. (2024). Research Progress and Controversy on the Relationship Between Iodine Excess and Thyroid Cancer Occurrence. American Journal of Health Research, 12(1), 1-7.

ACS Style

Feng, Z.; Na, L.; Guiran, Y. Research Progress and Controversy on the Relationship Between Iodine Excess and Thyroid Cancer Occurrence. Am. J. Health Res. 2024, 12(1), 1-7. doi: 10.11648/j.ajhr.20241201.11

AMA Style

Feng Z, Na L, Guiran Y. Research Progress and Controversy on the Relationship Between Iodine Excess and Thyroid Cancer Occurrence. Am J Health Res. 2024;12(1):1-7. doi: 10.11648/j.ajhr.20241201.11

Copyright © 2024 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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