,
Kiswendsida Pauline Yanogo,
Youssouf Traoré,
Nicaise Lepri Aka,
Djibril Barry,
Jean Kabore,
Smaîla Ouédraogo,
Nicolas Meda
Introduction: The emergence of multidrug-resistant tuberculosis (MDR-TB) is a challenge for disease control and prevention worldwide. Objective: To study factors associated with MDR-TB in patients diagnosed in the Centre region, from 2020 to 2022. Methods: We conducted a retrospective unpaired case-control study on data from January 1, 2020 to December 31, 2022. The variables used were grouped into sociodemographic, clinical, paraclinical and therapeutic characteristics. We calculated crude and adjusted odds ratios (aOR) at a 95% confidence interval (CI), with a significance level ɑ= 5%. Results: Factors associated with multidrug-resistant tuberculosis were history of TB treatment [OR=7.36; p=<0.0001]; place of residence [OR=6.04; p=0.0001]; alcohol consumption [OR=4.20, p=0.002]; Acid-Fast Bacillus (AFB) ≥ 3+ [OR=3.37, p=0.008]; hospitalization during treatment [OR=5.20; IC95%=1.79, p=0.002]; DOTS knowledge [OR=6.53; p=<0.0001]. Conclusion: Our study identified several factors associated with multidrug-resistant tuberculosis, those related to behavior in both patients and caregivers being: history of TB treatment; alcohol consumption; and lack of knowledge of the DOTS strategy. Which means that future studies should aim to understand the impact of patient behavior/knowledge or caregiver attitudes so that the results can guide the use of scarce resources to optimize their impact.
| Published in | Central African Journal of Public Health (Volume 11, Issue 3) |
| DOI | 10.11648/j.cajph.20251103.11 |
| Page(s) | 91-101 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2025. Published by Science Publishing Group |
Tuberculosis, Risk Factors, Multidrug-resistant Tuberculosis
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APA Style
Balima, C., Yanogo, K. P., Traoré, Y., Aka, N. L., Barry, D., et al. (2025). Factors Associated with Multidrug-Resistant Tuberculosis in Patients Diagnosed in the Centre Region, Burkina Faso, 2020-2022. Central African Journal of Public Health, 11(3), 91-101. https://doi.org/10.11648/j.cajph.20251103.11
ACS Style
Balima, C.; Yanogo, K. P.; Traoré, Y.; Aka, N. L.; Barry, D., et al. Factors Associated with Multidrug-Resistant Tuberculosis in Patients Diagnosed in the Centre Region, Burkina Faso, 2020-2022. Cent. Afr. J. Public Health 2025, 11(3), 91-101. doi: 10.11648/j.cajph.20251103.11
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Download@article{10.11648/j.cajph.20251103.11,
author = {Clarisse Balima and Kiswendsida Pauline Yanogo and Youssouf Traoré and Nicaise Lepri Aka and Djibril Barry and Jean Kabore and Smaîla Ouédraogo and Nicolas Meda},
title = {Factors Associated with Multidrug-Resistant Tuberculosis in Patients Diagnosed in the Centre Region, Burkina Faso, 2020-2022
},
journal = {Central African Journal of Public Health},
volume = {11},
number = {3},
pages = {91-101},
doi = {10.11648/j.cajph.20251103.11},
url = {https://doi.org/10.11648/j.cajph.20251103.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cajph.20251103.11},
abstract = {Introduction: The emergence of multidrug-resistant tuberculosis (MDR-TB) is a challenge for disease control and prevention worldwide. Objective: To study factors associated with MDR-TB in patients diagnosed in the Centre region, from 2020 to 2022. Methods: We conducted a retrospective unpaired case-control study on data from January 1, 2020 to December 31, 2022. The variables used were grouped into sociodemographic, clinical, paraclinical and therapeutic characteristics. We calculated crude and adjusted odds ratios (aOR) at a 95% confidence interval (CI), with a significance level ɑ= 5%. Results: Factors associated with multidrug-resistant tuberculosis were history of TB treatment [OR=7.36; p=Conclusion: Our study identified several factors associated with multidrug-resistant tuberculosis, those related to behavior in both patients and caregivers being: history of TB treatment; alcohol consumption; and lack of knowledge of the DOTS strategy. Which means that future studies should aim to understand the impact of patient behavior/knowledge or caregiver attitudes so that the results can guide the use of scarce resources to optimize their impact.
},
year = {2025}
}
TY - JOUR T1 - Factors Associated with Multidrug-Resistant Tuberculosis in Patients Diagnosed in the Centre Region, Burkina Faso, 2020-2022 AU - Clarisse Balima AU - Kiswendsida Pauline Yanogo AU - Youssouf Traoré AU - Nicaise Lepri Aka AU - Djibril Barry AU - Jean Kabore AU - Smaîla Ouédraogo AU - Nicolas Meda Y1 - 2025/05/29 PY - 2025 N1 - https://doi.org/10.11648/j.cajph.20251103.11 DO - 10.11648/j.cajph.20251103.11 T2 - Central African Journal of Public Health JF - Central African Journal of Public Health JO - Central African Journal of Public Health SP - 91 EP - 101 PB - Science Publishing Group SN - 2575-5781 UR - https://doi.org/10.11648/j.cajph.20251103.11 AB - Introduction: The emergence of multidrug-resistant tuberculosis (MDR-TB) is a challenge for disease control and prevention worldwide. Objective: To study factors associated with MDR-TB in patients diagnosed in the Centre region, from 2020 to 2022. Methods: We conducted a retrospective unpaired case-control study on data from January 1, 2020 to December 31, 2022. The variables used were grouped into sociodemographic, clinical, paraclinical and therapeutic characteristics. We calculated crude and adjusted odds ratios (aOR) at a 95% confidence interval (CI), with a significance level ɑ= 5%. Results: Factors associated with multidrug-resistant tuberculosis were history of TB treatment [OR=7.36; p=Conclusion: Our study identified several factors associated with multidrug-resistant tuberculosis, those related to behavior in both patients and caregivers being: history of TB treatment; alcohol consumption; and lack of knowledge of the DOTS strategy. Which means that future studies should aim to understand the impact of patient behavior/knowledge or caregiver attitudes so that the results can guide the use of scarce resources to optimize their impact. VL - 11 IS - 3 ER -
Population Health Prevention Department, Ministry of Health and Public Hygiene, Ouagadougou, Burkina Faso Burkina Field Epidemiology and Laboratory Training Program University Joseph Ki-Zerbo, Ouagadougou, Burkina Faso
Burkina Field Epidemiology and Laboratory Training Program University Joseph Ki-Zerbo, Ouagadougou, Burkina Faso Department of Public Health, Faculty of Medicine, University Joseph Ki-Zerbo, Ouagadougou, Burkina Faso
Department of Public Health and Medical Informatics, UFR Medical Sciences of Abidjan, Abidjan, Ivory Coast
Department of Public Health and Medical Informatics, UFR Medical Sciences of Abidjan, Abidjan, Ivory Coast
Burkina Field Epidemiology and Laboratory Training Program University Joseph Ki-Zerbo, Ouagadougou, Burkina Faso
Health Sciences Research Institute, National Center for Scientific and Technological Research, Ouagadougou, Burkina Faso
Department of Public Health, Faculty of Medicine, University Joseph Ki-Zerbo, Ouagadougou, Burkina Faso
Burkina Field Epidemiology and Laboratory Training Program University Joseph Ki-Zerbo, Ouagadougou, Burkina Faso
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