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Bilateral Nasosinusian Chondroblastoma: Case Study and Literature Review

Received: 29 September 2025     Accepted: 13 October 2025     Published: 31 October 2025
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Abstract

Chondroblastoma is a rare benign bone tumor, craniofacial localization is rarely reported in the literature. It accounts for 2 to 7% of all chondroblastomas. We report a case of nasosinusian chondroblastoma with bilateral involvement of the ethmoidal, sphenoidal and maxillary sinuses without lysis of the bones of the skull base. It was a 45-year-old patient, a housewife, who consulted us for a bilateral nasal obstruction with a clinical history dating back about six years, marked by a left unilateral nasal obstruction of progressive onset and permanent evolution, which bilateralized four months later. Other associated signs are bilateral rhinorrhea, anosmia, closed rhinolalia, and headache. Physical examination revealed swelling of the left cheek, regular, fixed, hard and painless contours. An endonasal mass completely obstructed both nasal cavities with a bulge of the palate. Maxillofacial CT revealed a bilateral, ethmoid and sphenoidal maxillary nasosinus mass of tissue density, osteolytic, containing lump-like calcifications of irregular outline. The surgical treatment, performed transpalatally in combination with the endonasal route, removed the entire mass. Histology concluded that there was a bilateral nasosinusian chondroblastoma. No recurrence after one year. Conclusion: Chondroblastoma is a rare tumor and its location in the head is extremely rare, difficult to detect at an early stage. Surgical excision is the therapeutic principle.

Published in Clinical Medicine Research (Volume 14, Issue 5)
DOI 10.11648/j.cmr.20251405.16
Page(s) 198-202
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Chondroblastoma, Tumors, Nasosinus

References
[1] Hadrien Stolza, Thierry Rod Fleurya, Sana Boudabbousb, Didier Hannouchea. Cartilaginous tumors. RevMed Switzerland 2018; 14: 2259-63.
[2] Rosenberg AE. WHO Classification of Soft Tissue and Bone, Fourth Edition: Summary and Commentary. Curr Opin Oncol. 2013; 25(5): 571-3.
[3] Douis H, Saifuddin A. Imaging of cartilage bone tumors. I. Benign lesions. Skeletal radiol. 2012; 41(10): 1195-212.
[4] Martinez AP, Mora JT. Selected lesions rich in giant cells of the temporal bone. Pathol Neck Head. 2018; 12(3): 367-77.
[5] Inward CY. Update on tumors forming the cartilage of the head and neck. Tête Cou Pathol. 2007; 1: 67-74.
[6] Muhammed A, Meshneb M, Saro H, Elnakib N, Elnakib E. Management of cranial chondroblastoma in adults; a pooled analysis. Am J Otolaryngol. 2020; 41: 102486.
[7] Liu J, Ahmadpour A, Bewley AF, Lechpammer M, Bobinski M, Shahlaie K. Chondroblastoma of the clivus: case report and review. J Neurol Surg Rep. 2015; 76: E258 to 64.
[8] Gavendra S, Kulkarni P, Shah K, Bradoo R. Chondroblastoma - a rare sinonasal tumor: case report and literature review. Int J Otorhinolaryngol Head Neck Surgery 2023 February; 9(2): 194-200.
[9] Cho SH, Yu IK, Kim SM, Kim JH, Lee SY. Chondroblastoma with secondary aneurysmal bone cyst in the sphenoidal sinus: a case report. J Korean Soc Radiol. 2017 Jan; 76(1): 61-66.
[10] Fazli M, Khajavi M, Mohammadi S, Zaker A, Jalili M, Davoodi F, Bazgir N, and Akbari N. Chondroblastoma located in the anterior base of the skull: a case report and a comprehensive review of the literature. Otolaryngology case reports. 2025; 9368865.
[11] Reid LB, Wong DS, Lyons B. Chondroblastoma of the temporal bone: a case series, a review and a suggested management strategy. Rep. of the skull base 2011; 1(2): 71-82.
[12] Fletcher CDM, Unni KK, Mertens F. Pathology and genetics of soft tissue and bone tumors. IARC Press, Lyon. 2013; 427.
[13] Sivaraju L, Kiran NAS, Ghosal N, Hegde AS. Chondroblastoma of the saddle and the base of the anterior cranial fossa. Clin Neuropathol. 2016; 35(1): 42-3.
[14] Wang MJ, Zhou B. Chondroblastoma with secondary aneurysmal bone cyst at the anterior base of the skull. Interdisciplinary neurosurgery. 2016; 4: 13-6.
[15] Cabrera RA, Almeida M, Mendonça ME, Frable WJ. Diagnostic pitfalls in fine needle aspiration cytology of temporomandibular chondroblastoma: report of two cases. Diagn Cytopathol. 2006; 34(6): 424-9.
[16] Kurokawa R, Uchida K, Kawase T. Surgical treatment of temporal bone chondroblastoma. Surg Neurol. 2005; 63(3): 265-8.
[17] Kurt AM, Unni KK, Sim FH, McLeod RA. Chondroblastoma of the bone. Pathol Buzz. 1989; 20(10): 965-76.
Cite This Article
  • APA Style

    Oumar, B. A., Tata, T., Issa, K. F., Oumar, K., Sadou, B., et al. (2025). Bilateral Nasosinusian Chondroblastoma: Case Study and Literature Review. Clinical Medicine Research, 14(5), 198-202. https://doi.org/10.11648/j.cmr.20251405.16

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    ACS Style

    Oumar, B. A.; Tata, T.; Issa, K. F.; Oumar, K.; Sadou, B., et al. Bilateral Nasosinusian Chondroblastoma: Case Study and Literature Review. Clin. Med. Res. 2025, 14(5), 198-202. doi: 10.11648/j.cmr.20251405.16

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    AMA Style

    Oumar BA, Tata T, Issa KF, Oumar K, Sadou B, et al. Bilateral Nasosinusian Chondroblastoma: Case Study and Literature Review. Clin Med Res. 2025;14(5):198-202. doi: 10.11648/j.cmr.20251405.16

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  • @article{10.11648/j.cmr.20251405.16,
      author = {Bagayoko Abdoulaye Oumar and Toure Tata and Kone Fatogoma Issa and Konate Oumar and Barry Sadou and Cisse Naouma and Dicko Ibrahim and Aichata Ouane and Assitan Kole Coulibaly and Diarra Kassim and Konate N'faly and Keita Mohamed Amadou},
      title = {Bilateral Nasosinusian Chondroblastoma: Case Study and Literature Review
    },
      journal = {Clinical Medicine Research},
      volume = {14},
      number = {5},
      pages = {198-202},
      doi = {10.11648/j.cmr.20251405.16},
      url = {https://doi.org/10.11648/j.cmr.20251405.16},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20251405.16},
      abstract = {Chondroblastoma is a rare benign bone tumor, craniofacial localization is rarely reported in the literature. It accounts for 2 to 7% of all chondroblastomas. We report a case of nasosinusian chondroblastoma with bilateral involvement of the ethmoidal, sphenoidal and maxillary sinuses without lysis of the bones of the skull base. It was a 45-year-old patient, a housewife, who consulted us for a bilateral nasal obstruction with a clinical history dating back about six years, marked by a left unilateral nasal obstruction of progressive onset and permanent evolution, which bilateralized four months later. Other associated signs are bilateral rhinorrhea, anosmia, closed rhinolalia, and headache. Physical examination revealed swelling of the left cheek, regular, fixed, hard and painless contours. An endonasal mass completely obstructed both nasal cavities with a bulge of the palate. Maxillofacial CT revealed a bilateral, ethmoid and sphenoidal maxillary nasosinus mass of tissue density, osteolytic, containing lump-like calcifications of irregular outline. The surgical treatment, performed transpalatally in combination with the endonasal route, removed the entire mass. Histology concluded that there was a bilateral nasosinusian chondroblastoma. No recurrence after one year. Conclusion: Chondroblastoma is a rare tumor and its location in the head is extremely rare, difficult to detect at an early stage. Surgical excision is the therapeutic principle.
    },
     year = {2025}
    }
    

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    T1  - Bilateral Nasosinusian Chondroblastoma: Case Study and Literature Review
    
    AU  - Bagayoko Abdoulaye Oumar
    AU  - Toure Tata
    AU  - Kone Fatogoma Issa
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    AU  - Barry Sadou
    AU  - Cisse Naouma
    AU  - Dicko Ibrahim
    AU  - Aichata Ouane
    AU  - Assitan Kole Coulibaly
    AU  - Diarra Kassim
    AU  - Konate N'faly
    AU  - Keita Mohamed Amadou
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    DO  - 10.11648/j.cmr.20251405.16
    T2  - Clinical Medicine Research
    JF  - Clinical Medicine Research
    JO  - Clinical Medicine Research
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    AB  - Chondroblastoma is a rare benign bone tumor, craniofacial localization is rarely reported in the literature. It accounts for 2 to 7% of all chondroblastomas. We report a case of nasosinusian chondroblastoma with bilateral involvement of the ethmoidal, sphenoidal and maxillary sinuses without lysis of the bones of the skull base. It was a 45-year-old patient, a housewife, who consulted us for a bilateral nasal obstruction with a clinical history dating back about six years, marked by a left unilateral nasal obstruction of progressive onset and permanent evolution, which bilateralized four months later. Other associated signs are bilateral rhinorrhea, anosmia, closed rhinolalia, and headache. Physical examination revealed swelling of the left cheek, regular, fixed, hard and painless contours. An endonasal mass completely obstructed both nasal cavities with a bulge of the palate. Maxillofacial CT revealed a bilateral, ethmoid and sphenoidal maxillary nasosinus mass of tissue density, osteolytic, containing lump-like calcifications of irregular outline. The surgical treatment, performed transpalatally in combination with the endonasal route, removed the entire mass. Histology concluded that there was a bilateral nasosinusian chondroblastoma. No recurrence after one year. Conclusion: Chondroblastoma is a rare tumor and its location in the head is extremely rare, difficult to detect at an early stage. Surgical excision is the therapeutic principle.
    
    VL  - 14
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Author Information
  • "Oumar Bagayoko" Medical Office, Regional Directorate of Health, Bamako, Mali

  • Department of ENT and Head and Neck Surgery of the Gabriel Touré University Hospital, University of Technical Sciences and New Technologies of Bamako (UTSTB), Bamako, Mali

  • Anatomy Laboratory of the Faculty of Medicine and Odontostomatology (FMOS), University of Technical Sciences and New Technologies of Bamako (UTSTB), Bamako, Mali

  • Anatomy Laboratory of the Faculty of Medicine and Odontostomatology (FMOS), University of Technical Sciences and New Technologies of Bamako (UTSTB), Bamako, Mali

  • Department of ENT and Head and Neck Surgery of the Gabriel Touré University Hospital, University of Technical Sciences and New Technologies of Bamako (UTSTB), Bamako, Mali

  • Anatomy Laboratory of the Faculty of Medicine and Odontostomatology (FMOS), University of Technical Sciences and New Technologies of Bamako (UTSTB), Bamako, Mali

  • Anatomy Laboratory of the Faculty of Medicine and Odontostomatology (FMOS), University of Technical Sciences and New Technologies of Bamako (UTSTB), Bamako, Mali

  • Anatomy Laboratory of the Faculty of Medicine and Odontostomatology (FMOS), University of Technical Sciences and New Technologies of Bamako (UTSTB), Bamako, Mali

  • Anatomy Laboratory of the Faculty of Medicine and Odontostomatology (FMOS), University of Technical Sciences and New Technologies of Bamako (UTSTB), Bamako, Mali

  • Anatomy Laboratory of the Faculty of Medicine and Odontostomatology (FMOS), University of Technical Sciences and New Technologies of Bamako (UTSTB), Bamako, Mali

  • Anatomy Laboratory of the Faculty of Medicine and Odontostomatology (FMOS), University of Technical Sciences and New Technologies of Bamako (UTSTB), Bamako, Mali

  • Anatomy Laboratory of the Faculty of Medicine and Odontostomatology (FMOS), University of Technical Sciences and New Technologies of Bamako (UTSTB), Bamako, Mali

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