Schistosomiasis remains a major public health problem in tropical countries and especially in DR Congo. One of the main preventive measures against trematode infection is the control of the disease vector population through the use of molluscicides. The objective of this work is focused on the fight against bilharzia intermediate host snails using extracts of the Neorautanenia mitis plant from the East of the Democratic Republic of Congo against the snails Biomphalaria pfeifferi intermediate host of bilharziasis. For the identification of the different characteristics of the plant, we used phytochemical tests based on color or precipitation reactions and a test of molluscicidal activities to know the lethal concentrations of the extracts were carried out. Analysis of the plant Neorautanenia mitis shows that this plant is pharmacologically active against snail intermediate hosts of bilharziasis. It contains phenol, terpene and saponin which are recognized as molluscicidal and insecticidal substances. The mortality rate is greater than 50% at a concentration of up to 0.002mg/L of the crude extracts in ethanol of this plant. This plant is very poisonous than these other plants. But the responsible substance is not yet well determined and deserves very detailed studies of the extraction of the different responsible substances and their tests on molluscs before determining the structure of this substance.
| Published in | International Journal of Pharmacy and Chemistry (Volume 11, Issue 6) |
| DOI | 10.11648/j.ijpc.20251106.11 |
| Page(s) | 113-118 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2025. Published by Science Publishing Group |
Molluscicidal Plant, Neorautanenia Mitis, Aqueous Extracts, Organic Extracts, Phytochemistry, Molluscicidal Activity
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APA Style
Bagalwa, J. J. M., Nshombo, P. K., Nfundiko, A. K., Karume, K. (2025). Evaluation of the Molluscicidal Activity of Aqueous and Ethanolic Extracts of the Neorautanenia Mitis Plant Against Snail Intermediate Hosts of Bilharziasis in the Laboratory. International Journal of Pharmacy and Chemistry, 11(6), 113-118. https://doi.org/10.11648/j.ijpc.20251106.11
ACS Style
Bagalwa, J. J. M.; Nshombo, P. K.; Nfundiko, A. K.; Karume, K. Evaluation of the Molluscicidal Activity of Aqueous and Ethanolic Extracts of the Neorautanenia Mitis Plant Against Snail Intermediate Hosts of Bilharziasis in the Laboratory. Int. J. Pharm. Chem. 2025, 11(6), 113-118. doi: 10.11648/j.ijpc.20251106.11
AMA Style
Bagalwa JJM, Nshombo PK, Nfundiko AK, Karume K. Evaluation of the Molluscicidal Activity of Aqueous and Ethanolic Extracts of the Neorautanenia Mitis Plant Against Snail Intermediate Hosts of Bilharziasis in the Laboratory. Int J Pharm Chem. 2025;11(6):113-118. doi: 10.11648/j.ijpc.20251106.11
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Download@article{10.11648/j.ijpc.20251106.11,
author = {Jean Jacques Mashimango Bagalwa and Prince Kilamwaka Nshombo and Antoine Kaguku Nfundiko and Katcho Karume},
title = {Evaluation of the Molluscicidal Activity of Aqueous and Ethanolic Extracts of the Neorautanenia Mitis Plant Against Snail Intermediate Hosts of Bilharziasis in the Laboratory},
journal = {International Journal of Pharmacy and Chemistry},
volume = {11},
number = {6},
pages = {113-118},
doi = {10.11648/j.ijpc.20251106.11},
url = {https://doi.org/10.11648/j.ijpc.20251106.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20251106.11},
abstract = {Schistosomiasis remains a major public health problem in tropical countries and especially in DR Congo. One of the main preventive measures against trematode infection is the control of the disease vector population through the use of molluscicides. The objective of this work is focused on the fight against bilharzia intermediate host snails using extracts of the Neorautanenia mitis plant from the East of the Democratic Republic of Congo against the snails Biomphalaria pfeifferi intermediate host of bilharziasis. For the identification of the different characteristics of the plant, we used phytochemical tests based on color or precipitation reactions and a test of molluscicidal activities to know the lethal concentrations of the extracts were carried out. Analysis of the plant Neorautanenia mitis shows that this plant is pharmacologically active against snail intermediate hosts of bilharziasis. It contains phenol, terpene and saponin which are recognized as molluscicidal and insecticidal substances. The mortality rate is greater than 50% at a concentration of up to 0.002mg/L of the crude extracts in ethanol of this plant. This plant is very poisonous than these other plants. But the responsible substance is not yet well determined and deserves very detailed studies of the extraction of the different responsible substances and their tests on molluscs before determining the structure of this substance.},
year = {2025}
}
TY - JOUR T1 - Evaluation of the Molluscicidal Activity of Aqueous and Ethanolic Extracts of the Neorautanenia Mitis Plant Against Snail Intermediate Hosts of Bilharziasis in the Laboratory AU - Jean Jacques Mashimango Bagalwa AU - Prince Kilamwaka Nshombo AU - Antoine Kaguku Nfundiko AU - Katcho Karume Y1 - 2025/12/11 PY - 2025 N1 - https://doi.org/10.11648/j.ijpc.20251106.11 DO - 10.11648/j.ijpc.20251106.11 T2 - International Journal of Pharmacy and Chemistry JF - International Journal of Pharmacy and Chemistry JO - International Journal of Pharmacy and Chemistry SP - 113 EP - 118 PB - Science Publishing Group SN - 2575-5749 UR - https://doi.org/10.11648/j.ijpc.20251106.11 AB - Schistosomiasis remains a major public health problem in tropical countries and especially in DR Congo. One of the main preventive measures against trematode infection is the control of the disease vector population through the use of molluscicides. The objective of this work is focused on the fight against bilharzia intermediate host snails using extracts of the Neorautanenia mitis plant from the East of the Democratic Republic of Congo against the snails Biomphalaria pfeifferi intermediate host of bilharziasis. For the identification of the different characteristics of the plant, we used phytochemical tests based on color or precipitation reactions and a test of molluscicidal activities to know the lethal concentrations of the extracts were carried out. Analysis of the plant Neorautanenia mitis shows that this plant is pharmacologically active against snail intermediate hosts of bilharziasis. It contains phenol, terpene and saponin which are recognized as molluscicidal and insecticidal substances. The mortality rate is greater than 50% at a concentration of up to 0.002mg/L of the crude extracts in ethanol of this plant. This plant is very poisonous than these other plants. But the responsible substance is not yet well determined and deserves very detailed studies of the extraction of the different responsible substances and their tests on molluscs before determining the structure of this substance. VL - 11 IS - 6 ER -
Department of Biology, Centre de Recherche en Sciences Naturelles, Lwiro, Democratic Republic of Congo;Faculté de Médecine, Université Evangélique en Afrique, Bukavu, République Démocratique du Congo
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