Special Issue
Submission Closed
Synthesis and Microbial Screening of Coordination and Organic Compounds
View Published Articles →01About This Special Issue
The discovery and development of antibiotics are among the most powerful and successful achievements of modern science and technology for the control of infectious diseases. However, the increasing microbial resistance to antibiotics in use nowadays necessitates the search for new compounds with potential effects against pathogenic bacteria. The most spectacular advances in medicinal chemistry have been made when nitrogen and sulphur containing compounds with heterocyclic, aromatic and heteroaromatic nucleus played an important role in regulating biological activities. When heterocyclic part like imidazole, nitromidazole etc. becomes attached to carbohydrate, their efficiency to inhibit fungus or bacteria sharply increased. Extensive investigations in the field of Schiff bases have been reported. Many Schiff bases are known to be medicinally important and are used to design medicinal compounds. Schiff bases appear to be an important intermediate in a number of enzymatic reactions involving interaction of an enzyme with an amino or a carbonyl group of the substrate. Schiff-base ligands with heterocyclic molecule and/or containing heteroatoms such as N, O, and S show a broad biological activity. Nitro and halo derivatives of Schiff bases are reported to have antimicrobial and antitumor activities. Schiff-base complexes are explored to DNA binding and cleavage and hence have been regarded as models for enzymes such as urease.We invite investigators to contribute original research articles as well as review articles focused on new synthesis in coordination and organic compounds and their microbial studies.
Potential topics include the following:
1. Synthesis and characterization of coordination compounds
2. Synthesis and characterization of organic compounds
3. Isolation and characterization of natural products
4. Their application in antimicrobial, antitumor, anticancer, DNA cleavage studies etc.
02Meet the Guest Editors
Our distinguished editors bring deep subject-matter expertise to curate high-quality research and ensure a rigorous peer-review process.
Lead Guest Editor
Mohammad Nasir
Department of Chemistry, University of Chittagong, Chittagong, Bangladesh
Guest Editor
Shreekant Deshpande
Analytical Department, Eutech Scientific Services, INC, Higland Park, United States
Guest Editor
Nikhil Madadi
University of Arkansas for Medical Sciences, United States
Guest Editor
Rajavel Rangappan
Department of Chemistry, Periyar University, Salem, India
Guest Editor
Md. Mosharef Hossain Bhuiyan
Department of Chemistry, University of Chittagong, Bangladesh, Bangladesh
03Published Articles
The following articles have been published in this special issue.
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Issue: Volume 3, Issue 1-1, January 2015Pages: 15-26Received: 11 October 2014Accepted: 13 February 2015Published: 27 February 2015DOI: 10.11648/j.mc.s.2015030101.13Downloads:Views:Abstract: A new ligand, 4-[carboxy-α-(2-hydroxyphenyl) ethylidene hydrazide-5,6-diphenyl-3(2H) pyridazinone (CHDP), were synthesized and characterized by 1H-NMR, IR spectra and elemental analysis. The dissociation equilibrium constant of CHEDP as well as the equilibrium constant for different M+n-CHEDP complexes were reported at different temperatures in 75... Show More -
Pb(II) Complexes of Schiff Bases Derived from Benzoylhydrazine as the Antibacterial Agents
Issue: Volume 3, Issue 1-1, January 2015Pages: 7-14Received: 20 December 2014Accepted: 23 December 2014Published: 27 January 2015DOI: 10.11648/j.mc.s.2015030101.12Downloads:Views:Abstract: Some Pb(II) complexes of dibasic tridentate Schiff base ligands derived from aldehydes/ketones and benzoylhydrazine have been synthesized and characterized by some physico-chemical studies; elemental, spectral (IR, UV, NMR, Mass), magnetic, and conductance analyses. The CHN elemental analysis data showed the formation of 1:1 [M:L] complexes. The ob... Show More -
Issue: Volume 3, Issue 1-1, January 2015Pages: 1-6Received: 18 December 2014Accepted: 25 December 2014Published: 27 January 2015DOI: 10.11648/j.mc.s.2015030101.11Downloads:Views:Abstract: A number of bimetallic thiocyanato-bridged complexes of cations [M(NH2X)6]2+ and [M(en)3]2+ with anions [Co(NCS)4]2– are prepared. Their structure has been investigated in terms of FT-IR, 13C NMR and UV-vis spectroscopy, metal analysis, magnetic and conductance studies. The complexes are proposed to have the following compositions, [M(NH2X)5][Co(NC... Show More
