Molecular Diagnosis of Rickettsia aeschlimannii in Febrile Patients in Côte d’Ivoire:: Science Publishing Group

Molecular Diagnosis of Rickettsia aeschlimannii in Febrile Patients in Côte d’Ivoire

Fidèle N’guessan Diobo^1,2, Amenan Claude Aimée Kouamé Diaha³, Yahaya Sylla², Grace Rebecca Bogni¹, Valery Edgard Adjogoua², Hortense Kette Faye⁴, Mireille Dosso⁵, Patrick Kouassi Yao⁶

Corresponding Author: Fidèle N’guessan Diobo

¹Biology and Health Laboratory, Felix Houphouët-Boigny University, Abidjan, Côte d’Ivoire

²Vector-Borne Virus Unit, Institute Pasteur of Côte d’Ivoire, Abidjan, Côte d’Ivoire

³Environment and Health Department, Institute Pasteur of Côte d’Ivoire, Abidjan, Côte d’Ivoire

⁴Genital Tract Agents Unit, Institute Pasteur of Côte d’Ivoire, Abidjan, Côte d’Ivoire

⁵Bacteriology Virology Department, Institute Pasteur of Côte d’Ivoire, Abidjan, Côte d’Ivoire

⁶Animal Parasitology Laboratory, Alassane Ouattara University, Bouaké, Côte d'Ivoire

American Journal of BioScience, Volume 11, Issue 6, November 2023

Pages: 137-141

Received: Sep. 26, 2023

Accepted: Oct. 24, 2023

Published: Nov. 09, 2023

DOI: 10.11648/j.ajbio.20231106.11

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Abstract

R aeschlimannii is a bacterium that causes Mediterranean spotted fever. It is a rickettsial disease, which is an acute febrile illness characterized by the appearance of skin pimples and bedsores. R. aeschlimannii is mainly transmitted by ticks of the genus Hyalomma, which are present throughout the African continent, including Côte d’Ivoire. Despite the presence of the pathogen and its potential vectors in Côte d'Ivoire, the disease is not yet well-known or even undiagnosed in our health centers. Consequently, it is a neglected disease. The aim of this study is to search for R. aeschlimannii bacteria in febrile patients in order to improve the management of febrile illnesses in Côte d’Ivoire. Blood samples taken from patients to test for yellow fever virus and stored in the Institut Pasteur of Côte d’Ivoire biobank were also used to test for R. aeschlimannii by quantitative PCR. The 5 to 14-year-olds patients from Korhogo were infested with R. aeschlimannii with a relatively low prevalence of 9.10%. Our results underline the need to continue the study to control certain tick-borne diseases transmitted to both animals and humans. In the north of the country, the age group most vulnerable to Mediterranean spotted fever is the pre-adolescent age.

Keywords

Rickettsia aeschlimannii, Mediterranean Spotted Fever, Ticks, Febrile Patients, Côte d’Ivoire

To cite this article

Fidèle N’guessan Diobo, Amenan Claude Aimée Kouamé Diaha, Yahaya Sylla, Grace Rebecca Bogni, Valery Edgard Adjogoua, et al. (2023). Molecular Diagnosis of Rickettsia aeschlimannii in Febrile Patients in Côte d’Ivoire. American Journal of BioScience, 11(6), 137-141. https://doi.org/10.11648/j.ajbio.20231106.11

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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