American Journal of BioScience

Volume 11, Issue 6, November 2023

  • Research Article

    Molecular Diagnosis of Rickettsia aeschlimannii in Febrile Patients in Côte d’Ivoire

    Fidèle N’guessan Diobo*, Amenan Claude Aimée Kouamé Diaha, Yahaya Sylla, Grace Rebecca Bogni, Valery Edgard Adjogoua, Hortense Kette Faye, Mireille Dosso, Patrick Kouassi Yao

    Issue: Volume 11, Issue 6, November 2023
    Pages: 137-141
    Received: Sep. 26, 2023
    Accepted: Oct. 24, 2023
    Published: Nov. 09, 2023
    DOI: 10.11648/j.ajbio.20231106.11
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    Abstract: R aeschlimannii is a bacterium that causes Mediterranean spotted fever. It is a rickettsial disease, which is an acute febrile illness characterized by the appearance of skin pimples and bedsores. R. aeschlimannii is mainly transmitted by ticks of the genus Hyalomma, which are present throughout the African continent, including Côte d’Ivoire. Despi... Show More
  • Research Article

    Construction of a Clinical Prediction Model for Systemic Sclerosis Cuproptosis-Related Genes Using Machine Learning

    Xinmin Huang, Xu Cai, Xinpeng Chen, Yiwei Hong, Zhengbo Yan, Jianwei Xiao*

    Issue: Volume 11, Issue 6, November 2023
    Pages: 142-149
    Received: Oct. 31, 2023
    Accepted: Nov. 15, 2023
    Published: Nov. 24, 2023
    DOI: 10.11648/j.ajbio.20231106.12
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    Abstract: Objective: This study aims to identify cuproptosis-related genes in Systemic Sclerosis (SSc) and construct a clinical prediction model. Methods: The GSE33463 dataset was retrieved from the GEO database, and gene set enrichment analysis (GSEA) was used to analyze the expression of pathways related to cuproptosis. Cuproptosis-related genes were extra... Show More