International Journal of Nutrition and Food Sciences

Special Issue

Analytical and Microbiological Characterization of Antimicrobial Peptides

  • Submission Deadline: 30 December 2016
  • Status: Submission Closed
  • Lead Guest Editor: Ivanka Pencheva-El Tibi
About This Special Issue
The increasing antibiotic resistance of pathogenic bacteria requires promptly resolutions for the development of alternative antimicrobial therapies. Possible approaches include the development of novel specific formulations including antimicrobial peptides as well as broad-spectrum antibiotics.

Antimicrobial peptides, which have been isolated from many bacteria, fungi and plants, are an important component of the natural defenses of most living organisms. The isolated peptides are very heterogeneous in length, sequence and structure, but most of them are small, cationic and amphipathic. These peptides exhibit broad-spectrum activity against Gram-positive and Gram-negative bacteria, fungi and viruses. A wide variety of human proteins and peptides also has antimicrobial activity and plays important roles in innate immunity. They have been considered for potential use in the medicinal therapy. Despite of this there is rather limited clinical applications of antimicrobial peptides and a number questions without answers in the scientific area from one side and the society expectation about new drugs against infection diseases from the other hand.

Aims and Scope:

1. Antimicrobial peptides – structure, production, purification and biological activities.
2. Analytical characterization of antimicrobial peptide molecules in different matrices. Application of chromatographic and spectral methods.
3. Peptide antibiotics – specific aspects in producing of formulations and quality control.
4. Antimicrobial peptides as potential new agents against predominated drug-resistance bacteria.
5. Naturally occurring peptides – isolation and characterization.
Lead Guest Editor
  • Ivanka Pencheva-El Tibi

    Department of Pharmaceutical chemistry, Faculty of Pharmacy,Medical University, Sofia, Bulgaria

Guest Editors
  • Vania Maslarska

    Department Chemistry, Medical University, Sofia, Bulgaria

Published Articles
  • Evaluate the Productive and Reproductive Performance Considering Genotypes of Dairy Cows

    Md. Akhtarul Islam , Md. Jalal Uddin Sarder , Syed Sarwar Jahan , Md. Hemayatul Islam

    Issue: Volume 5, Issue 6-1, December 2016
    Pages: 10-15
    Received: 20 December 2016
    Accepted: 5 January 2017
    Published: 20 March 2017
    DOI: 10.11648/j.ijnfs.s.2016050601.13
    Abstract: Progress of production in dairy cattle is frequently considered possible by either improving the genetic merit and/or by husbandry practices. The aim of the research is to evaluation of productive and reproductive performance of dairy cows considering genotype was undertaken in greater Rajshahi from July, 2007 to June, 2009. A total 335 farmers dat... Show More
  • Antimicrobial Peptides with Plant Origin

    Zdraveva Petranka , Yotova Maya , Kaloyanov Kaloyan , Pencheva Ivanka

    Issue: Volume 5, Issue 6-1, December 2016
    Pages: 5-9
    Received: 14 March 2016
    Accepted: 16 March 2016
    Published: 8 December 2016
    DOI: 10.11648/j.ijnfs.s.2016050601.12
    Abstract: According to the World Health Organization plants are one of the best sources to obtain a huge variety of biologically active compounds. Human population during centuries has used plants and plants extracts in ethno medicine to cure wide range of diseases. In the scope of modern methods of isolation and purification of different plant substances, a... Show More
  • Antimicrobial Peptides Past, Present and Future

    Yotova Maya , Kaloyanov Kaloyan , Petar Donchev , Zdraveva Petranka , Pencheva Ivanka

    Issue: Volume 5, Issue 6-1, December 2016
    Pages: 1-4
    Received: 5 January 2016
    Accepted: 6 January 2016
    Published: 18 October 2016
    DOI: 10.11648/j.ijnfs.s.2016050601.11
    Abstract: Uncontrolled antibiotic use lead to increasing the level of resistant bacterial species. Antimicrobial peptides (AMPs) are one of the few alternatives in the fight with everyday growing bacterial resistance to commonly used antibiotics. AMPs general application could be also as endotoxin neutralizing agents or as an adjuvants to regular antimicrobi... Show More