Review Article
The Impact of Radiation on Breast Cancer Treatment (Case Study: Breast Cancer)
Issue:
Volume 13, Issue 4, December 2025
Pages:
91-95
Received:
18 May 2025
Accepted:
12 September 2025
Published:
17 October 2025
DOI:
10.11648/j.jctr.20251304.11
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Abstract: Radiation therapy has long been established as a cornerstone in oncological practice and remains one of the most effective modalities in the management of malignant diseases. It is a specialized field within oncology that utilizes high-energy ionizing radiation, such as X-rays or gamma rays, with the objective of eradicating cancer cells while preserving adjacent healthy tissues. This dual aim of maximizing tumor control and minimizing normal tissue toxicity underscores the critical importance of precision in treatment planning and delivery. The present study specifically examines the role of radiation therapy in the management of breast cancer, which represents one of the most prevalent malignancies among women globally. Given the availability of multiple therapeutic strategies—including surgical resection, systemic chemotherapy, hormonal interventions, immunotherapy, and targeted therapies—radiation therapy occupies a distinct position in ensuring local tumor control and reducing recurrence. This study employs a descriptive-analytical approach, drawing upon a broad review and synthesis of experimental and clinical investigations to evaluate the therapeutic efficacy and limitations of radiation therapy in breast cancer treatment. The findings consistently demonstrate that radiation therapy exerts a markedly positive effect on patient outcomes, particularly in reducing local recurrence rates, improving disease-free survival, and contributing to overall survival. However, the therapeutic impact is contingent upon several decisive factors. These include the accuracy of tumor delineation, the radiation oncologist’s ability to identify and mitigate potential errors during planning and delivery, the reduction of scattered radiation beyond the treatment field, and the maintenance of a homogeneous dose distribution across the target volume. Optimization of these parameters is essential to achieving favorable clinical results while limiting acute and long-term side effects. In conclusion, radiation therapy continues to serve as an indispensable modality in the multidisciplinary management of breast cancer. Ongoing advances in imaging technologies, treatment planning algorithms, and delivery systems, such as intensity-modulated radiotherapy and image-guided radiotherapy, are expected to further enhance the precision, safety, and clinical effectiveness of this therapeutic approach. Collectively, these developments underscore the enduring and evolving role of radiation therapy in improving survival outcomes and quality of life for breast cancer patients.
Abstract: Radiation therapy has long been established as a cornerstone in oncological practice and remains one of the most effective modalities in the management of malignant diseases. It is a specialized field within oncology that utilizes high-energy ionizing radiation, such as X-rays or gamma rays, with the objective of eradicating cancer cells while pres...
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,
Fatemeh Sangsefidi
